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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35557 | CK2 inhibitor 2 | Casein Kinase | |
CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM. It exhibits high selectivity towards Clk2 with an IC50 of 32.69 nM in compariso... | |||
T7390 | DMAT | Casein kinase II Inhibitor,CK2 Inhibitor | Casein Kinase |
DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM). | |||
T2259 | Silmitasertib | CX-4945 | Casein Kinase , Autophagy |
Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM). | |||
T2695 | TBB | Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole | GSK-3 , Casein Kinase , CDK |
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2). | |||
T10827 | CK2/ERK8-IN-1 | TMCB | Apoptosis , ERK , Casein Kinase , Pim , DYRK |
CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25... | |||
T1828 | TTP 22 | Casein Kinase | |
TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM, and shows selectivity >250-fold for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM). | |||
T9356 | (E/Z)-GO289 | Casein Kinase | |
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function... | |||
T69307 | IQA | ||
IQA is a casein kinase 2 (CK2) inhibitor. | |||
T71627 | CX-5011 | Casein Kinase | |
CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2]. | |||
T63991 | BRD4/CK2-IN-1 | ||
BRD4/CK2-IN-1 is the first potent, orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), acting on both BRD4 (IC50: 180 nM) and CK2 (IC50: 230 nM). In triple-negative breast ... | |||
T21642 | 4,5,6,7-Tetrabromobenzimidazole | ||
4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1]. | |||
T79908 | ON 108600 | Casein Kinase | |
ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, ... |